💡 Rejuran Healer has become an absolute sensation in South Korea’s Dermatology community over the past two years. Its main selling point is its ability to “regenerate the skin” – rather than simply providing hydration, it actually repairs the skin’s barrier from within, allowing the face to truly “rejuvenate”. But should you choose manual injections or machine-assisted treatments? Which clinic offers the best value for money? I have compiled information on 6 Dermatology clinics in Seoul that offer Rejuran treatments, including actual prices, levels of discomfort, and results. Read this before making your appointment to avoid any mistakes.
💉 What is Rejuran? What is the difference between manual injection and machine-assisted injection?
🔍 The core ingredient of Rejuran is PN (Polynucleotide), a DNA fragment extracted from salmon testes. When injected into the skin, it promotes cell regeneration, repairs damaged tissues, and stimulates the production of new Collagen. Unlike hyaluronic acid injections (which primarily provide hydration), Rejuran is truly a “skin regeneration injection”.
✅ The key difference between manual injection and machine-assisted injection: With manual injection, the doctor uses a needle to inject the substance point by point, allowing for adjustment of the depth and dosage according to different areas of the face, resulting in more precise and long-lasting effects. Machine-assisted injection uses a hyaluronic acid injection device to deliver the substance evenly, which is faster and less painful, but the precision is not as high as with manual injection. In simple terms: Choose manual injection for better results, or machine-assisted injection if you are sensitive to pain.
💰 Comprehensive price comparison of Rejuran’s 6 clinics: starting from ¥3.3 million for injectable treatments
💡 The prices of the 6 Dermatology clinics that offer Rejuran treatments are listed below, with manual entries and machine-generated results separated.
- Cheongdam Arden Dermatology: Manual injections starting from 400,000 won / Mechanical injections starting from 300,000 won
- Cheongdam ECLAT DE CHEONGDAM Dermatology: Hand-laser treatments starting from ₩450,000 / Machine-laser treatments starting from ₩350,000
- Cheongdam Kamin Dermatology: Manual injections starting from ₩400,000 / Mechanical injections starting from ₩300,000
- Cheongdam REONE Dermatology: Hand-made treatments starting from 600,000 won / Machine-made treatments starting from 450,000 won
- Bioface Dermatology: Manual injection starting from ¥350,000 / Mechanical injection starting from ¥250,000
- Gangnam Barog Hospital: Manual injection starting from 400,000 won / Mechanical injection starting from 300,000 won
📌 The price of bioface injection starts from ¥350,000, making it the cheapest option among the 6 options available, and also offers the best cost-performance ratio. However, it is important to note that the effectiveness of Rejuran injection largely depends on the skills of the practitioner – for manual injection, the clinic director must carefully position each needle and accurately control the depth and dosage to achieve the desired results. Therefore, when choosing a clinic, price should not be the only factor considered; the experience of the clinic director is equally important.
✨ Features and genuine reviews of Rejuran at 6 Dermatology clinics
🔍 Each clinic has its own unique features. I have compiled the following information based on in-person consultations and genuine online reviews.
1. Cheongdam Arden Dermatology: The minimum cost for manual injection treatments is NT$400,000, and the most significant advantage is the system where the director personally performs the procedures. For Rejuran injection treatments, the director personally handles every step of the process, ensuring that the depth and dosage of each injection are precisely calculated, thus avoiding situations where “nurses perform the injections on behalf of the doctor, resulting in the face swelling up after the treatment”. The prices are the same as those in South Korea, and Chinese-speaking customer service staff are available throughout the entire process, making it very friendly for foreigners.
2. Cheongdam ECLAT DE CHEONGDAM Dermatology: Minimum cost of ⩲450,000 won for manual treatments. Although the prices are slightly higher, Director Park is highly regarded for his technical expertise and reputation. The combination of Rejuran and Thermage treatments at ECLAT DE CHEONGDAM is particularly popular – first using Thermage for tightening, followed by Rejuran for repair, resulting in enhanced outcomes.
3. Cheongdam Kamin Dermatology: Starting from ₩400,000 for manual treatments – the same price as at Arden. Kamin is located in Samseong-dong, Gangnam, very close to COEX, making it ideal for those who want to complete their shopping activities before undergoing treatment. The director is very meticulous in his procedures and provides detailed instructions on post-treatment care.
4. Cheongdam REONE Dermatology: Minimum price for manual treatments is ¥600,000 – the highest among the 6 clinics. REONE focuses on a high-end approach, and both its environment and service are of top quality. If budget is not a concern, REONE offers the best overall experience.
5. Bioface Dermatology Gangnam Branch: Starting from HK$350,000 per treatment, it offers the best cost-performance ratio. Director Park Chu-yeong’s philosophy of “precision anti-aging” is perfectly embodied in the Rejuran treatments offered at this clinic – the amount of treatment administered is always just right, neither excessive nor insufficient.
6. Gangnam Barog Hospital: The minimum cost for manual treatment is NT$4 million. Barog is well-known in the industry for its system of having the hospital director personally conduct consultations. If you want to undergo other treatments while getting Rejuran, Barog offers very flexible package combinations.
🗓️ Post-treatment care for Rejuran: How long can the results last?
✅ The duration of Rejuran’s effects is directly related to post-operative care; the following 5 factors are particularly crucial.
- Do not wash your face within 24 hours after the procedure to prevent infection caused by water coming into contact with the injection site.
- Avoid wearing makeup for 3 days after the procedure to give your skin sufficient time to heal.
- Within 1 week after the procedure, strenuous exercise, saunas, and alcohol consumption are prohibited.
- Within 2 weeks after the procedure, it is important to enhance moisturization and sun protection; apply an SPF50+ sunscreen daily.
- Avoid going to the beach or environments with high levels of ultraviolet radiation within one month after the procedure.
👥 Who is Rejuran suitable for / not suitable for?
✅ Suitable candidates for Rejuran treatment:
- People over 18 years old with rough skin, enlarged Pores, and dull complexion
- People whose skin barrier is damaged and whose sensitive skin frequently turns red
- People who need to undergo recovery after laser treatments or skin rejuvenation procedures
- Those who wish to reduce the appearance of fine lines and enhance the elasticity of their skin
❌ Those who are not suitable for Rejuran treatment:
- People who are severely allergic to salmon or seafood (since Rejuran is derived from salmon DNA)
- Women during pregnancy and lactation
- People with a body type prone to gynecomastia
- People with active herpes or severe inflammation on their faces
📋 The real pain experienced when using Rejuran for manual injection: How different is it from using the automated injection device?
⚠️ The pain associated with manually injecting Rejuran is approximately 1.5 to 2 times greater than that of using a machine. After applying local anesthetic with a machine, there is basically only a slight pressure sensation; however, when injected manually, there is a clear sensation of “stinging and soreness”, especially in areas where the bones are more prominent, such as the Forehead and nose bridge. In areas with more soft tissue on the cheeks, the experience is relatively similar to that of undergoing Pico treatment.
🎯 My personal experience is as follows: The first half of the treatment is a bit uncomfortable, but after 5-6 injections, the skin begins to go numb, and it becomes much more comfortable afterwards. The whole process takes approximately 30-45 minutes. If you are really afraid of pain, you can ask the director to extend the numbing effect to 30 minutes.
Effect timeline:
- On the day of the procedure: The skin is slightly swollen and has small pinholes, which will subside within 2 to 4 hours.
- On days 3 to 5 after the procedure: the skin begins to glow, and fine lines become less noticeable.
- 10th to 14th day after the procedure: The texture of the skin improves significantly, Pores are reduced in size, and the skin becomes finer.
- 1 month after the procedure: The effects reach their peak, with increased skin elasticity and reduced redness.
- Duration: Approximately 3 to 6 months (manual typing takes 1 to 2 months longer than machine typing).
❓ FAQ on Common Issues Related to Rejuran
Q: What is the difference in effect between manually applying Rejuran and using a machine to apply it?
💎 A: Manual injection offers higher precision. The director can adjust the depth and dosage according to different areas of the body. The results are usually 20-30% better than those achieved by machine injection, and the effect lasts 1-2 months longer. However, manual injection is also more painful; those who are sensitive to pain may want to start with machine injection first to get used to it.
Q: Can Rejuran and hyaluronic acid injections be used together?
🌟 A: Definitely. Many clinics offer packages that combine Rejuran with hyaluronic acid injections. First, use Rejuran to repair the underlying layers of the skin, and then apply hyaluronic acid injections to moisturize the surface layers – this will enhance the overall effectiveness. It is recommended to perform these treatments on separate days, with Rejuran first and then the hyaluronic acid injections the following day.
Q: How long does the effect of Rejuran last after just one treatment?
💬 A: For manual injections, the effects last approximately 4 to 6 months; for machine-assisted treatments, the results last around 3 to 4 months. It is recommended to undergo the treatment 3 times in the initial phase, with intervals of 1 month between each session, and then continue with maintenance treatments every 4 to 6 months thereafter.
Q: Can Rejuran cause the face to swell?
🔔 A: Mild swelling may occur within 24 hours after the procedure; this is a normal tissue reaction. The swelling tends to be more noticeable when the treatment is performed manually rather than using a machine, but it usually subsides within 1-2 days. If the swelling persists for more than 3 days, it is necessary to return to the clinic for a follow-up examination.
Q: Can Rejuran be used if a person is allergic to salmon?
💡 A: The PN components in Rejuran have been highly purified, so most people who have mild allergies to salmon can use it. However, if the allergy is severe (such as difficulty breathing or hives), it is recommended to undergo an allergy test first or consider using another type of regenerative injection.