If you are researching medical aesthetics in Busan, you have a high chance of coming across Busan JRYN Dermatology. This clinic enjoys a decent reputation in South Korea and has recently begun attracting many tourists from Taiwan and Hong Kong who make special trips just to visit it. As for my own visit this time, it was mainly for one specific reason: the hand-administered Rejuran treatment (Juvelook).
The ingredient Rejuran is not unfamiliar to us, but the debate over whether it should be prepared manually or by machine has remained unresolved in various communities. Taking this trip to South Korea as an opportunity, I decided to personally experience the manual preparation method at JRYN and compare it with my previous experiences using the machine-made version. The following is a complete and authentic record of my experience.
The location and surroundings of JRYN Dermatology in Busan

JRYN Dermatology is located in the vicinity of Seomyeon Station in Busan, just a 5-minute walk from the subway exit. The clinic is small in size, but its interior is designed in a clean and minimalist Japanese style, giving visitors an immediate sense of relaxation—a stark contrast to the luxurious and oppressive atmosphere of some clinics in Seoul.
The waiting area offers Chinese-speaking consultation services, and the staff will proactively ask whether you are from Taiwan or Hong Kong, so there are basically no communication barriers. The reservation process supports Line, and the response times are quite fast, making it easy to coordinate your schedule. The clinic also provides on-site tax refund services, which is very considerate of overseas visitors.
📍 Address: 4th Floor, Mitsui Tower, 672 Jungang-daero, Busan Town Area, Busan (3 minutes’ walk from Ex
it 2 of Seomyeon Station) 🕐 Hours of operation: Monday to Friday 10:30–20:00, Saturday 10:30–14:30
What is Rejuran? Why is it the subject of so much discussion?

Rejuran (Juvelook) is a composite skin repair injectable containing PDLLA (poly-L-lactic acid) microspheres and Filler. Once it enters the dermis, it gradually stimulates the production of Collagen while providing immediate moisturizing effects. The results are not immediate, but the duration of these effects is longer than that of traditional hyaluronic acid injections. It is generally recommended to use this treatment every 1–2 months, with 3–4 sessions constituting one course of treatment.
There are two ways to apply Rejuran:
- Machine-assisted injection (Meso Gun): The substance is evenly administered through a negative-pressure automatic injection device, allowing for dense application at high speed, making it ideal for large-area improvements.
- Manual injection: The doctor manually injects the substance at each specific point, allowing for adjustments to the depth and dosage based on the individual’s skin condition. This method offers greater precision but relies more on the doctor’s technical skills, and the procedure takes longer.
Theoretically, typing by hand is more delicate, but most people report that it hurts much more than typing on a keyboard. This is precisely the core issue I wanted to verify personally this time.
Consultation section: What do the doctors at Busan JRYN Dermatology have to say about manual injections versus machine-assisted injections?

Before the actual procedure, the director personally conducted a skin assessment and provided consultation, offering very specific recommendations based on my needs—specifically, reducing fine lines and improving the overall quality of my skin.
- Suitable for those with decent skin foundations who primarily want to hydrate and maintain moisture. The treatment involves dense and even application, making it ideal for large areas and quick procedures. It causes less discomfort and has a short recovery time.
- Hand-held devices are suitable for individuals with specific localized areas in need of treatment, such as fine lines around the eyes, Nasolabial Fold Correction, or the areas on both sides of the nose. Doctors can adjust the depth and dosage according to the condition of the skin, resulting in more significant local improvement effects.
The director also explained directly that the injection method does indeed produce a more noticeable effect, especially in areas with thinner skin, such as the cheekbones and around the eyes, where there may be a distinct stinging sensation. It is recommended to apply an anesthetic cream in advance or to opt for a injectable version containing local anesthetics. Since my main concern were the fine lines around my eyes, I ultimately decided to go with the full-face injection treatment.
Actual experience using Rejuran injected manually at Busan JRYN Dermatology: Is it really more painful than when injected by machine?

Let me state the conclusion first: It hurts, but not to an extent that it’s unbearable.
The treatment is applied to the entire face, including the Forehead, Apple Zone, under-eye areas, both sides of the nose, and the chin. After applying the anesthetic cream for approximately 20 minutes, the procedure begins, and the entire treatment takes around 35 minutes.
Regional Pain Scale (out of 10):
- Forehead area: Approximately 3/10 of the area; there is only a slight stinging sensation, and the pain is relatively mild.
- The Apple Zone and the cheeks: Approximately a ratio of 5:10. There is a slight stinging sensation, but it’s not excessive and can be easily tolerated.
- The area below the nose: Approximately 7 out of 10. This is the most painful part of the entire procedure, especially in the thin skin area below the nose – every single injection caused a distinct stinging sensation. Instinctively, I furrowed my brows several times, but overall, the pain was still tolerable.
- Jaw area: Approximately 4/10 – it’s much better than before, especially in the areas where the skin is slightly thicker.
Compared to my previous experience with machine-assisted injections (which took about 4-5 minutes in total), manual injection does feel more noticeable, but it’s not to the point where I would say “never do it again.” If you are particularly sensitive to pain, I suggest letting your doctor know so that they can adjust the injection technique or administer additional anesthesia if necessary.
Immediate effects and recovery process after treatment at Busan JRYN Dermatology

After the treatment, obvious red spots and mild swelling appeared on the face immediately, which are normal reactions to the injections. The nurses at JRYN would apply ice packs for about 10 minutes after the procedure, and the discomfort would be significantly reduced. Here is the complete timeline for recovery:
- On the same day: The face was red, slightly swollen, and the needle holes were clearly visible; it was not suitable to attend important events. It is recommended to return to the hotel and rest.
- Day 2: The red spots begin to fade, but there is still a slight swelling, and the skin feels a bit tight to the touch. It is not recommended to wear makeup at this time.
- On days 3–4: The needle holes have basically healed, and the skin feels glower than before the treatment; the Pores also appear to have reduced in size visually.
- Day 7: Entering a stable phase, my skin looks much more plump. A colleague even asked if I had been getting enough sleep lately – the results are indeed visible to the naked eye.
- On the 30th day: Collagen continues to proliferate, resulting in significantly reduced fine lines under the eyes and improved overall skin elasticity.
Comparison of the effects of JRYN Dermatology in Busan: Is manual treatment really better than machine-assisted treatment?

Overall, the precision of manual typing in specific areas is indeed superior to that of machine typing. This is especially true for the area that has been bothering me for some time; the improvement observed one week later was significantly greater than what I had experienced with machine typing before. The trade-offs, however, are more noticeable pain and a slightly longer recovery period. For those who have specific needs for localized improvements, the cost-effectiveness of manual typing is quite high.
Reference fees for JRYN Dermatology

JRYN strictly adheres to the policy of equal prices for Chinese and foreign customers and does not charge additional fees just because the customer is a foreign tourist. The following are the reference fees (subject to variations depending on the treatment area and the amount of injectable substances used):
- Full-face Rejuran injection (2 centum cores): Approximately 400,000–500,000 Korean won (equivalent to approximately NT$9,000–11,000)
- Cost of anesthetic cream: It is usually included in the package and is not charged separately.
- Postoperative care (ice compress + soothing facial mask): Included in the fee.
- On-site tax refund: We support tax refunds, allowing overseas travelers to save some costs.
Compared with similar treatments in Taiwan and Hong Kong (the cost of Rejuran injections ranges from NT$15,000 to NT$25,000), the price in South Korea offers a significant advantage. If you plan your trip accordingly, the overall cost-effectiveness is quite high.
People who are suitable for receiving Rejuran injections at Busan’s JRYN Dermatology clinic

Based on this comprehensive experience, the following types of people are particularly suitable for choosing to have Rejuran injections at JRYN:
- ✅ Those who require targeted and precise improvements in specific areas (fine lines around the eyes, Nasolabial Fold Correction, the areas beside the nostrils)
- ✅ For those who are not satisfied with the results of machine-generated text and want to experience the difference of manual typing
- ✅ Overseas travelers who need to communicate in Chinese but prefer not to rely on translations
- ✅ For those whose itinerary includes Busan and who wish to experience South Korea’s medical beauty services along the way
- ✅ For those who value transparent pricing and prefer not to be bombarded with excessive sales pitches
Situations where it may not be quite suitable: For those who are extremely sensitive to pain or have a very tight schedule (it is recommended to reserve 2–3 days for recovery after the procedure), it is advisable to undergo a preliminary assessment or opt for a non-invasive treatment option.

My experience with manual Rejuran injections at JRYN in Busan exceeded my expectations. The clinic environment was welcoming, the doctor communicated carefully, and the post-treatment care was excellent. Although manual injections are indeed more painful than automated ones, the resulting local improvement is much more noticeable, making it absolutely worth it for those with specific needs.
If you’re also struggling with the decision between manual and machine injections, my advice is to choose based on your skin’s specific needs and your tolerance for pain, rather than simply following the trend. During your consultation, be sure to tell the doctor about the area that concerns you so they can provide a personalized treatment plan tailored to your needs.
I hope this honest account can be of some help to those of you who are considering undergoing medical beauty treatments in Busan! If you have any questions, please feel free to leave a comment below, and I will do my best to respond 🌸
Frequently Asked Questions
Q: Does Busan JRYN Dermatology provide services in Chinese?
A: Yes, JRYN provides Chinese translation services. You can make an online reservation through BeautsGO, and upon arrival at the store, Chinese staff will be available to assist you with communication – so even if you don’t speak Korean, it’s completely no problem.
Q: Is JRYN Dermatology a clinic where the director personally sees patients?
A: Yes, JRYN implements a one-to-one consultation system where Dr. Jin personally handles all consultations and procedures, rather than relying on a team-based division of labor.
Q: Is it painful to have Rejuran injections at JRYN?
A: After applying the anesthetic, the pain is significantly reduced. However, areas with bony protrusions such as the Forehead and nose bridge experience noticeable soreness and swelling, while the soft tissues of the cheeks remain relatively comfortable. Overall, it’s still tolerable, and the results are definitely worth it.
Q: How long does the effect of Rejuran last?
A: The effects of Rejuran usually last for 3 to 6 months. It is recommended to return for a follow-up examination after 3 months to determine whether a booster dose is needed. The results achieved through manual injection are more lasting than those obtained by machine injection, but the pain associated with manual injection is also slightly greater.
Q: Are the evaluations of Dermatology clinics in South Korea trustworthy? How can one tell whether they are genuine or not?
A: It is recommended to compare reviews from Naver, Dcard, and Google. If a platform receives too many positive reviews, it is worth paying attention. Genuine reviews usually contain specific details (such as pain levels, the procedure itself, and post-treatment changes), while template-based positive reviews are often fabricated.
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