💡 Rejuran Healer has become an absolute sensation in South Korea’s Dermatology community over the past two years. Its main selling point is its ability to “regenerate the skin” – rather than simply providing hydration, it actually repairs the skin’s barrier from within, allowing the face to truly “rejuvenate”. But should you choose manual treatments or machine-assisted procedures? Which clinic offers the best value for money? I’ve compiled a list of 6 Dermatology clinics in Seoul that offer Rejuran treatments, including real prices, information on discomfort levels, and results. Read this before making your appointment to avoid any surprises.
💉 What is Rejuran? What exactly is the difference between manual and machine-made versions?
🔍 The core component of Rejuran is PN (Polynucleotide), a DNA fragment extracted from salmon testes. When injected into the skin, it promotes cell regeneration, repairs damaged tissues, and stimulates the production of new Collagen. Unlike hyaluronic acid injections (which primarily provide hydration), Rejuran is truly a “skin regeneration injection”.
✅ The key difference between manual injection and machine-assisted injection: Manual injection is performed by the clinic director using a needle to inject the substance point by point, allowing for precise adjustment of the depth and dosage according to different areas of the face, resulting in more accurate and long-lasting effects. Machine-assisted injection uses a hyaluronic acid injection device to deliver the substance evenly, which is faster and less painful, but the accuracy is not as high as with manual injection. In simple terms: Choose manual injection for better results, or machine-assisted injection if you are sensitive to pain.
💰 Comprehensive price comparison of Rejuran’s 6 clinics: starting from ¥3.3 million for manual treatments
💡 The prices of the 6 Dermatology clinics that offer Rejuran treatments are listed below, with manual entries and machine-generated results separated separately.
- Cheongdam Arden Dermatology: Manual injections starting from ₩400,000 / Mechanical injections starting from ₩300,000
- Cheongdam ECLAT DE CHEONGDAM Dermatology: Hand-laser treatments starting from ₩450,000 / Machine-laser treatments starting from ₩350,000
- Cheongdam Kamin Dermatology: Manual injections starting from ₩400,000 / Mechanical injections starting from ₩300,000
- Cheongdam REONE Dermatology: Manual injections starting from ₩600,000 / Mechanical injections starting from ₩450,000
- Bioface Dermatology: Manual injection starting from ₩350,000 / Mechanical injection starting from ₩250,000
- Gangnam Barog Hospital: Manual injections starting from 400,000 won / Mechanical injections starting from 300,000 won
📌 The price of bioface injection starts from ¥350,000, making it the cheapest option among the six available options, and also offers the best cost-performance ratio. However, it is important to note that the effectiveness of Rejuran injections largely depends on the skills of the practitioner – for manual injections, the clinic director must carefully position each needle and accurately control the depth and dosage to achieve optimal results. Therefore, when choosing a clinic, price should not be the only consideration; the experience of the clinic director is equally important.
✨ Features and genuine reviews of Rejuran’s 6 Dermatology clinics
🔍 Each clinic has its own unique features. Based on in-person consultations and genuine online reviews, I have compiled the following information.
1. Cheongdam Arden Dermatology: Starting from ¥4.4 million for manual injections, the chief physician’s personal consultation service is its greatest advantage. The entire Rejuran injection process is performed by the chief physician himself, with the depth and dosage of each injection carefully calculated to ensure that there is no risk of “nurses performing the injections on behalf of the doctor, resulting in the face swelling up after treatment.” The prices are the same as those in South Korea, and Chinese-speaking customer service is available throughout the process, making it very friendly towards foreigners.
2. Cheongdam ECLAT DE CHEONGDAM Dermatology: Starting from ₩4.5 million for manual treatments, the prices are slightly higher, but Director Park is highly regarded for his technical expertise. The combination of Rejuran and Thermage treatments at ECLAT DE CHEONGDAM is particularly popular – first using Thermage for tightening, followed by Rejuran for repair, resulting in enhanced outcomes.
3. Cheongdam Kamin Dermatology: Starting from ₩400,000 for manual treatments – the same price as at Arden. Kamin is located in Samseong-dong, Gangnam, very close to COEX, making it ideal for a quick treatment after shopping. The director is very meticulous during the procedure and provides detailed instructions on post-treatment care.
4. Cheongdam REONE Dermatology: Starting from ₩600,000 for manual treatments, it is the most expensive among the 6 options available. REONE focuses on a high-end approach, and both its environment and service are of top quality. If budget is not a concern, REONE offers the best overall experience.
5. Bioface Dermatology Gangnam Branch: Starting from a minimum investment of ¥350,000 per treatment, it offers the highest cost-performance ratio. Director Park Chu-yeong’s philosophy of “precision anti-aging” is perfectly embodied in the Rejuran treatments offered at this clinic – the amount of treatment administered is always just right, neither excessive nor insufficient.
6. Gangnam Barog Hospital: The minimum cost for manual treatment starts at ¥4 million. Barog is well-known in the industry for its system of having the hospital director personally conduct consultations. If you want to undergo other treatments while getting Rejuran, Barog offers very flexible package combinations.
🗓️ Post-treatment care for Rejuran: How long can the results last?
✅ The duration of Rejuran’s effects is directly related to post-operative care; the following 5 factors are particularly crucial.
- Do not wash your face within 24 hours after the procedure to prevent infection caused by water coming into contact with the injection site.
- Avoid wearing makeup for 3 days after the procedure to give your skin sufficient time to heal.
- Within 1 week after the procedure, strenuous exercise, saunas, and alcohol consumption are strictly prohibited.
- Within 2 weeks after the procedure, it is important to enhance moisturization and sun protection; apply an SPF50+ sunscreen daily.
- Avoid going to the beach or environments with high levels of ultraviolet radiation within one month after the procedure.
👥 Who is Rejuran suitable for / not suitable for?
✅ Suitable candidates for Rejuran treatment:
- People over 18 years old with rough skin, enlarged Pores, and dull complexion
- Those whose skin barrier is damaged and whose sensitive skin frequently turns red
- Those who have undergone laser treatments or skin rejuvenation procedures and need recovery time
- Those who want to reduce the appearance of fine lines and enhance the elasticity of their skin
❌ Those who are not suitable for Rejuran treatment:
- People who are severely allergic to salmon or seafood (since Rejuran is derived from salmon DNA)
- Women during pregnancy and lactation
- People with a body type prone to crab leg edema
- People with active herpes or severe inflammation on their faces
📋 Rejuran’s firsthand experience of the actual pain during injection: How much difference is there compared to automated injection methods?
⚠️ The pain associated with manually injecting Rejuran is approximately 1.5 to 2 times greater than that of using a machine. When injected using a machine and local anesthetic is applied, there is basically only a slight pressure sensation; however, manual injection causes a distinct “stinging” and “aching” feeling, especially in areas where the bones are more prominent, such as the Forehead and nose bridge. In areas with more soft tissue on the cheeks, the experience is somewhat similar to that of undergoing Pico treatment.
🎯 My personal experience is as follows: The first half of the procedure is a bit uncomfortable, but after 5-6 injections, my skin begins to feel numb, making the rest of the process much more comfortable. The entire procedure takes approximately 30-45 minutes. If you are really afraid of pain, you can ask the doctor to extend the numbing effect to 30 minutes.
Effect timeline:
- On the day of the procedure: The skin appears slightly swollen and has small needle holes, which will subside within 2 to 4 hours.
- On days 3 to 5 after the procedure: The skin begins to glow with a moist sheen, and fine lines appear less noticeable.
- 10–14 days after the procedure: The texture of the skin improves significantly; Pores are reduced, and the skin becomes smoother.
- One month after the procedure: The effects reach their peak – the skin’s elasticity increases, and redness diminishes.
- Duration: Approximately 3 to 6 months (manual typing takes 1 to 2 months longer than using a keyboard).
❓ FAQ on Common Issues Regarding Rejuran
Q: What is the difference in effect between manually applying Rejuran and using a machine to apply it?
💎 A: Manual injection offers higher precision. The director can adjust the depth and dosage according to different areas of the body. The results are usually 20-30% better than those achieved by machine injection, and the effect lasts 1-2 months longer. However, manual injection is also more painful, so those who are sensitive to pain may want to start with machine injection first to get used to it.
Q: Can Rejuran and hyaluronic acid injections be used together?
🌟 A: Definitely. Many clinics offer packages that combine Rejuran with hyaluronic acid injections. First, use Rejuran to repair the underlying layers of the skin, and then apply hyaluronic acid injections to moisturize the surface layers – this combination enhances the effectiveness significantly. It is recommended to schedule these treatments on separate days, with Rejuran first and the hyaluronic acid injections the following day.
Q: How long does the effect of Rejuran last after just one application?
💬 A: Manual tattooing takes approximately 4 to 6 months, while machine tattooing takes around 3 to 4 months. It is recommended to get the tattoo done 3 times in the initial phase, with intervals of 1 month between each session, and then maintain it every 4 to 6 months thereafter.
Q: Can Rejuran cause the face to swell?
🔔 A: Mild swelling may occur within 24 hours after the procedure; this is a normal tissue reaction. Manual injections tend to cause more swelling than machine-assisted ones, but it usually subsides within 1-2 days. If the swelling persists for more than 3 days, you should return to the clinic for a follow-up examination.
Q: Can I use Rejuran if I am allergic to salmon?
💡 A: The PN components in Rejuran have been highly purified, so most people who have mild allergies to salmon can use it. However, if you have severe allergies (such as difficulty breathing or hives), it is recommended to undergo an allergy test first or consider using other regenerative injections instead.
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